Functional Segregation of Human Brain Networks Across the Lifespan: An Exploratory Analysis of Static and Dynamic Resting-State Functional Connectivity.

ABSTRACT: Prior research has shown that during development, there is increased segregation between, and increased integration within, prototypical resting-state functional brain networks. Functional networks are typically defined by static functional connectivity over extended periods of rest. However, little is known about how time-varying properties of functional networks change with age. Likewise, a comparison of standard approaches to functional connectivity may provide a nuanced view of how network integration and segregation are reflected across the lifespan. Therefore, this exploratory study evaluated common approaches to static and dynamic functional network connectivity in a publicly available dataset of subjects ranging from 8 to 75 years of age. Analyses evaluated relationships between ag

SUBMITTER: Rosenberg BM 

PROVIDER: S-EPMC7752769 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature