Effects of Extended Postmortem Interval on Microbial Communities in Organs of the Human Cadaver.

ABSTRACT: Human thanatomicrobiota studies have shown that microorganisms inhabit and proliferate externally and internally throughout the body and are the primary mediators of putrefaction after death. Yet little is known about the source and diversity of the thanatomicrobiome or the underlying factors leading to delayed decomposition exhibited by reproductive organs. The use of the V4 hypervariable region of bacterial 16S rRNA gene sequences for taxonomic classification ("barcoding") and phylogenetic analyses of human postmortem microbiota has recently emerged as a possible tool in forensic microbiology. The goal of this study was to apply a 16S rRNA barcoding approach to investigate variation among different organs, as well as the extent to which microbial associations among different body organs

SUBMITTER: Lutz H 

PROVIDER: S-EPMC7752770 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature