Novel Risk Factors for Progression of Diabetic and Nondiabetic CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

ABSTRACT:

Rationale & objective

Identification of novel risk factors for chronic kidney disease (CKD) progression may inform mechanistic investigations and improve identification of high-risk subgroups. The current study aimed to characterize CKD progression across levels of numerous risk factors and identify independent risk factors for CKD progression among those with and without diabetes.

Study design

The Chronic Renal Insufficiency Cohort (CRIC) Study is a prospective cohort study of adults with CKD conducted at 7 US clinical centers.

Setting & participants

Participants (N=3,379) had up to 12.3 years of follow-up; 47% had diabetes.

Predictors

30 risk factors for CKD progression across sociodemographic, behavioral, clinical, and biochemical domains at baseline.

Out

SUBMITTER: Anderson AH 

PROVIDER: S-EPMC7752839 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature