Risk of selection bias due to non-participation in a cohort study on pubertal timing.

ABSTRACT:

Background

Non-participation in aetiologic studies of pubertal timing is frequent. However, little effort has been given to explore the risk and potential impact of selection bias in studies of pubertal timing.

Objective

We aimed to explore the risk of selection bias due to non-participation in a newly established puberty cohort.

Methods

We evaluated whether three maternal exposures chosen a priori (pre-pregnancy obesity, smoking, and alcohol drinking during pregnancy) were associated with participation, whether pubertal timing was associated with participation, and whether selection bias influenced the associations between these exposures and pubertal timing. In total, 22 439 children from the Danish National Birth Cohort born 2000-2003 were invited to the Puberty Co

SUBMITTER: Brix N 

PROVIDER: S-EPMC7754153 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature