Cognitive Function During Opioid Tapering in Patients with Chronic Pain: A Prospective Cohort Study.

ABSTRACT:

Purpose

Evidence for efficacy and safety lacks for long-term opioid therapy in patients with chronic non-cancer pain and adverse effects, including affection of cognitive function and quality of life, is of concern. We aimed to investigate cognitive function and health-related quality of life in patients with chronic non-cancer pain during opioid reduction.

Patients and methods

At two multidisciplinary pain centers, all patients with planned opioid reduction were screened for eligibility. Cognitive function was assessed using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and Trail Making Test A and B. Health-related quality of life was assessed using Short Form-36 (SF36) and Hospital Anxiety and Depression Scale (HADS).

Results

We incl

SUBMITTER: Laigaard J 

PROVIDER: S-EPMC7754260 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature