Chronic post-operative opioid use after open cardiac surgery: A Danish population-based cohort study.

ABSTRACT:

Background

Knowledge of chronic opioid use after cardiac surgery is sparse. We therefore aimed to describe the proportion of new chronic post-operative opioid use after open cardiac surgery.

Methods

We used prospectively registered data from a national prescription registry and a clinical registry of 29 815 first-time cardiac surgeries from three Danish university hospitals. Data collection spanned from 2003 to 2016. The main outcome was chronic post-operative opioid use, defined as at least one opioid dispensing in the fourth post-operative quarter. Data were assessed for patient-level predictors of chronic post-operative opioid use, including pre-operative opioid use, opioid use at discharge, comorbidities, and procedural related variables.

Results

The overall propo

SUBMITTER: Bonnesen K 

PROVIDER: S-EPMC7754369 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature