In Vivo ¹ H MR Spectroscopy of Biliary Components of Human Gallbladder at 7T.

ABSTRACT:

Background

Previous in vivo proton MR spectroscopy (MRS) studies have demonstrated the possibility of quantifying amide groups of conjugated bile acids (NHCBA), olefinic lipids and cholesterol (OLC), choline-containing phospholipids (CCPLs), taurine and glycine conjugated bile acids (TCBA, GCBA), methylene group of lipids (ML), and methyl groups of bile acids, lipids, and cholesterol (BALC1.0, BALC0.9, and TBAC) in the gallbladder, which may be useful for the study of cholestatic diseases and cholangiopathies. However, these studies were performed at 1.5T and 3T, and higher magnetic fields may offer improved spectral resolution and signal intensity.

Purpose

To develop a method for gallbladder MRS at 7T.

Study type

Retrospective, technical development.

Population

SUBMITTER: Gajdosik M 

PROVIDER: S-EPMC7754442 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature