Automated Assessment of Cerebral Arterial Perforator Function on 7T MRI.

ABSTRACT:

Background

Blood flow velocity and pulsatility of small cerebral perforating arteries can be measured using 7T quantitative 2D phase contrast (PC) MRI. However, ghosting artifacts arising from subject movement and pulsating large arteries cause false positives when applying a previously published perforator detection method.

Purpose

To develop a robust, automated method to exclude perforators located in ghosting artifacts.

Study type

Retrospective.

Subjects

Fifteen patients with vascular cognitive impairment or carotid occlusive disease and 10 healthy controls.

Field strength/sequence

7T/cardiac-gated 2D PC MRI.

Assessment

Perforators were automatically excluded from ghosting regions, which were defined as bands in the phase-encoding direction of

SUBMITTER: Arts T 

PROVIDER: S-EPMC7754489 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature