Incidence of congestive heart failure in rheumatoid arthritis: a review of literature and meta-regression analysis.

ABSTRACT:

Aims

Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disorder that not only affects peripheral joints but also increases the risk for cardiovascular disease (CVD) and mortality. Heart failure (HF) appears to be one of the most important contributors to the excess mortality risk among patients with RA. We assessed the incidence of HF in patients with RA compared with age-matched and sex-matched non-RA subjects, after accounting for traditional cardiovascular risk factors and clinical ischemic heart disease.

Methods and results

We performed an aggregate analysis on three studies of RA patients having listed manifestations of HF. We performed a meta-regression analysis to evaluate the incidence of HF in RA patients with increased age and noted for any gender cor

SUBMITTER: Khalid Y 

PROVIDER: S-EPMC7754742 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature