Impact of right ventricular contractile reserve during low-load exercise on exercise intolerance in heart failure.

ABSTRACT:

Aims

Traditional criteria for heart transplantation by cardiopulmonary exercise testing (CPX) include peak oxygen uptake (VO₂ ) < 14 mL/kg/min. Reaching a sufficient exercise load is challenging for patients with refractory heart failure (HF) because of their exercise intolerance. Recently, a substantial impact of right ventricular (RV) dysfunction was highlighted on urgent heart transplantation and mortality. This study aims to investigate the impact of RV contractile reserve, assessed by low-load exercise stress echocardiography (ESE), on exercise intolerance defined as peak VO₂  < 14 mL/kg/min, in patients with HF.

Methods and results

We prospectively examined 67 consecutive patients hospitalized for HF who underwent ESE and CPX under a stabilized HF

SUBMITTER: Kinoshita M 

PROVIDER: S-EPMC7755000 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature