Investigating and reducing the effects of confounding factors for robust T₁ and T₂ mapping with cardiac MR fingerprinting.

ABSTRACT: This study aims to improve the accuracy and consistency of T₁ and T₂ measurements using cardiac MR Fingerprinting (cMRF) by investigating and accounting for the effects of confounding factors including slice profile, inversion and T₂ preparation pulse efficiency, and B₁⁺. The goal is to understand how measurements with different pulse sequences are affected by these factors. This can be used to determine which factors must be taken into account for accurate measurements, and which may be mitigated by the selection of an appropriate pulse sequence. Simulations were performed using a numerical cardiac phantom to assess the accuracy of over 600 cMRF sequences with different flip angles, TRs, and preparation pulses. A subset of sequences,

SUBMITTER: Hamilton JI 

PROVIDER: S-EPMC7755105 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature