Ontology highlight
ABSTRACT:
SUBMITTER: Scholich A
PROVIDER: S-EPMC7755288 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Scholich André A Syga Simon S Morales-Navarrete Hernán H Segovia-Miranda Fabián F Nonaka Hidenori H Meyer Kirstin K de Back Walter W Brusch Lutz L Kalaidzidis Yannis Y Zerial Marino M Jülicher Frank F Friedrich Benjamin M BM
PLoS computational biology 20201210 12
How epithelial cells coordinate their polarity to form functional tissues is an open question in cell biology. Here, we characterize a unique type of polarity found in liver tissue, nematic cell polarity, which is different from vectorial cell polarity in simple, sheet-like epithelia. We propose a conceptual and algorithmic framework to characterize complex patterns of polarity proteins on the surface of a cell in terms of a multipole expansion. To rigorously quantify previously observed tissue- ...[more]