Association Between Peripheral Blood Cell Count Abnormalities and Health-Related Quality of Life in the General Population.

ABSTRACT: Complete blood cell counts, including differentials, are widely available and change on aging. Peripheral blood cell counts outside the normal range have previously been associated with increased mortality rates and a number of comorbid conditions. However, data about the association between blood cell count abnormalities, other than anemia, and health-related quality of life (HRQoL) are scarce. We investigated the association between abnormalities in (differential) blood cell counts and HRQoL in 143 191 community-dwelling individuals from the prospective population-based Lifelines cohort. HRQoL was measured using the RAND 36-Item Health Survey. Logistic regression analyses were used to determine the effect of blood cell count abnormalities on the odds of having a lower score than an age-

SUBMITTER: Wouters HJCM 

PROVIDER: S-EPMC7755519 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature