Association of Optical Coherence Tomography With Longitudinal Neurodegeneration in Veterans With Chronic Mild Traumatic Brain Injury.

ABSTRACT:

Importance

Mild traumatic brain injury (TBI) may predispose individuals to progressive neurodegeneration.

Objective

To identify evidence of neurodegeneration through longitudinal evaluation of changes in retinal layer thickness using optical coherence tomography in veterans with a history of mild TBI.

Design, setting, and participants

This longitudinal cohort study evaluated veterans who were receiving services at the Minneapolis Veterans Affairs Health Care System. Symptomatic or mild TBI was diagnosed according to the Mayo TBI Severity Classification System. Participants in the age-matched control group had no history of TBI. Participants with any history or evidence of retinal or optic nerve disease that could affect retinal thickness were excluded. Data analysis w

SUBMITTER: Gilmore CS 

PROVIDER: S-EPMC7756235 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature