Association of First Primary Cancer With Risk of Subsequent Primary Cancer Among Survivors of Adult-Onset Cancers in the United States.

ABSTRACT:

Importance

The number of cancer survivors who develop new cancers is projected to increase, but comprehensive data on the risk of subsequent primary cancers (SPCs) among survivors of adult-onset cancers are limited.

Objective

To quantify the overall and cancer type-specific risks of SPCs among adult-onset cancer survivors by first primary cancer (FPC) types and sex.

Design, setting, and participants

A retrospective cohort study from 12 Surveillance, Epidemiology, and End Results registries in the United States, that included 1 537 101 persons aged 20 to 84 years diagnosed with FPCs from 1992-2011 (followed up until December 31, 2017) and who survived at least 5 years.

Exposures

First primary cancer.

Main outcomes and measures

Incidence and mortality of S

SUBMITTER: Sung H 

PROVIDER: S-EPMC7756242 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature