Facile and Reliable Emission-Based Nanomolar Anion Sensing by Luminescent Iridium Receptors Featuring Chelating Halogen-Bonding Sites.

ABSTRACT: An anion sensor is presented that combines a bidentate hydrogen- (HB) or halogen-bonding (XB) site with a luminescent monocationic Ir fragment for strong binding of common anions (K_a up to 6×10⁴  m^-1 ) with diagnostic emission changes. A new emission-based protocol for fast and reliable detection was derived on the basis of correction for systematic but unspecific background effects. Such a simple correction routine circumvents the hitherto practical limitations of systematic emission-based analysis of anion binding with validated open-source software (BindFit). The anticipated order of K_a values was obeyed according to size and basicity of the anions (Cl>Br=OAc) as well as the donor atom of the receptor (XB: 6×10⁴  m^-1 > HB

SUBMITTER: Kampes R 

PROVIDER: S-EPMC7756348 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature