Trends in HbA_1c thresholds for initiation of hypoglycemic agents: Impact of changed recommendations for older and frail patients.

ABSTRACT:

Aims

Less strict glycated hemoglobin (HbA_1c ) thresholds have been recommended in older and/or frail type 2 diabetes (T2D) patients than in younger and less frail patients for initiating hypoglycemic agents since 2011. We aimed to assess trends in HbA_1c thresholds at initiation of a first hypoglycemic agent(s) in T2D patients and the influence of age and frailty on these trends.

Materials and methods

The groningen initiative to analyze type 2 diabetes treatment (GIANTT) database was used, which includes primary care T2D patients from the north of the Netherlands. Patients initiating a first non-insulin hypoglycemic agent(s) between 2008 and 2014 with an HbA_1c measurement within 120 days before initiation were included. The influence of calend

SUBMITTER: Ambroz M 

PROVIDER: S-EPMC7756585 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature