Rates of Vascular Events in Patients With Migraine: A MarketScan^® Database Retrospective Cohort Study.

ABSTRACT:

Objective

To estimate the baseline rates of vascular events among people with migraine.

Background

Several novel medications that target the calcitonin gene-related peptide (CGRP) pathway are approved to treat people with migraine. Given that the CGRP pathway also plays a role in maintaining cardiovascular homeostasis, determining the baseline rates of vascular events among people with migraine will help inform the safety of these novel medications.

Methods

In this retrospective cohort study, patients 18- to 64-year-old patients with migraine were identified from the MarketScan^® database (January 2013-December 2017) and were categorized into 4 vascular risk categories: migraine with aura; and high, medium, and low vascular risk. Event rates (per 1000 person

SUBMITTER: Gill K 

PROVIDER: S-EPMC7756746 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature