Blood pressure, antihypertensive medication and neuropsychiatric symptoms in older people with dementia: The COSMOS study.

ABSTRACT:

Objectives

Neuropsychiatric symptoms (NPS) are very common in older patients with dementia. There is increasing evidence that hypoperfusion of the brain plays a role in the development of NPS. The aim of this study is to assess whether there is an association between low systolic blood pressure (SBP) and NPS and if NPS are more prevalent in older people with dementia using antihypertensive medication.

Methods

We studied the baseline data from participants in the Communication, Systematic pain treatment, Medication review, Organized activities and Safety study, a multicenter clustered trial with 765 participants from 72 nursing home units from 37 nursing homes in Norway. SBP (lowest quartile vs rest) and use of antihypertensive medication were predictors and Neuropsychiatric

SUBMITTER: de Jong-Schmit BEM 

PROVIDER: S-EPMC7756813 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature