A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota.

ABSTRACT: Not getting enough sleep is a common problem in our society and contributes to numerous health problems, including high blood pressure, diabetes and obesity. Related to these observations, a wealth of studies has underscored the negative impact of both acute and chronic sleep deprivation on cognitive function. More recently it has become apparent that the gut microbiota composition can be rapidly altered, modulates brain function and is affected by the aforementioned health problems. As such, changes in the microbiota composition may contribute to the behavioural and physiological phenotypes associated with sleep deprivation. It is unclear, however, whether a brief period of sleep deprivation can also negatively impact the gut microbiota. Here, we examined the impact of 5 hr of sleep depri

SUBMITTER: El Aidy S 

PROVIDER: S-EPMC7757181 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature