Inflammatory bowel disease in sub-Saharan Africa: a protocol of a prospective registry with a nested case-control study.

ABSTRACT:

Introduction

The epidemiology of inflammatory bowel disease (IBD) in sub-Saharan Africa is poorly documented. We have started a registry to determine the burden, phenotype, risk factors, disease course and outcomes of IBD in Zimbabwe.

Methods and analysis

A prospective observational registry with a nested case-control study has been established at a tertiary hospital in Harare, Zimbabwe. The registry is recruiting confirmed IBD cases from the hospital, and other facilities throughout Zimbabwe. Demographic and clinical data are obtained at baseline, 6 months and annually. Two age and sex-matched non-IBD controls per case are recruited-a sibling or second-degree relative, and a randomly selected individual from the same neighbourhood. Cases and controls are interviewed for pot

SUBMITTER: Katsidzira L 

PROVIDER: S-EPMC7757438 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature