Assessment of the sublingual microcirculation with the GlycoCheck system: Reproducibility and examination conditions.

ABSTRACT:

Background

The glycocalyx is an extracellular layer lining the lumen of the vascular endothelium, protecting the endothelium from shear stress and atherosclerosis and contributes to coagulation, immune response and microvascular perfusion. The GlycoCheck system estimates glycocalyx' thickness in vessels under the tongue from perfused boundary region (PBR) and microvascular perfusion (red blood cell (RBC) filling) via a camera and dedicated software.

Objectives

Evaluating reproducibility and influence of examination conditions on measurements with the GlycoCheck system.

Methods

Open, randomised, controlled study including 42 healthy smokers investigating day-to-day, side-of-tongue, inter-investigator variance, intraclass-correlation (ICC) and influence of examination c

SUBMITTER: Eickhoff MK 

PROVIDER: S-EPMC7757800 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature