Abnormal Aortic Wall Properties in Women with Turner Syndrome.

ABSTRACT:

Background

 Turner syndrome (TS) is associated with aortic dilatation and dissection, but the underlying process is unclear. The aim of this study was to investigate the elastic properties and composition of the aortic wall in women with TS.

Methods

 In this cross-sectional study, 52 women with TS aged 35 ± 13 years (50% monosomy, 12 with bicuspid aortic valve [BAV] and 4 with coarctation) were investigated using carotid-femoral pulse wave velocity (CF-PWV) by echocardiography and ascending aortic distensibility (AAD) and aortic arch pulse wave velocity (AA-PWV) by magnetic resonance imaging (MRI). As control group, 13 women with BAV without TS and 48 healthy patients were included.

Results

 Women with TS showed a higher AA-PWV (β = 1.08, confidence interval [CI]: 0.5

SUBMITTER: Bons LR 

PROVIDER: S-EPMC7758113 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature