Clinical Decision Support System with Renal Dose Adjustment Did Not Improve Subsequent Renal and Hepatic Function among Inpatients: The Japan Adverse Drug Event Study.

ABSTRACT:

Background

Medication dose adjustment is crucial for patients with renal dysfunction (RD). The assessment of renal function is generally mandatory; however, the renal function may change during the hospital stay and the manual assessment is sometimes challenging.

Objective

We developed the clinical decision support system (CDSS) that provided a recommended dose based on automated calculated renal function.

Methods

We conducted a prospective cohort study in a single teaching hospital in Japan. All hospitalized patients were included except for obstetrics/gynecology and pediatric wards between September 2013 and February 2015. The CDSS was implemented on December 2013. Renal and hepatic dysfunction (HD) were defined as changes in the estimated glomerular filtration rate

SUBMITTER: Wada R 

PROVIDER: S-EPMC7758157 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature