A Hematological-Related Prognostic Scoring System for Patients With Newly Diagnosed Glioblastoma.

ABSTRACT:

Background

Glioblastoma is the most common primary malignant brain tumor. Recent studies have shown that hematological biomarkers have become a powerful tool for predicting the prognosis of patients with cancer. However, most studies have only investigated the prognostic value of unilateral hematological markers. Therefore, we aimed to establish a comprehensive prognostic scoring system containing hematological markers to improve the prognostic prediction in patients with glioblastoma.

Patients and methods

A total of 326 patients with glioblastoma were randomly divided into a training set and external validation set to develop and validate a hematological-related prognostic scoring system (HRPSS). The least absolute shrinkage and selection operator Cox proportional hazards r

SUBMITTER: Zhao C 

PROVIDER: S-EPMC7758450 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature