Systematic Analysis of Expression Profiles and Prognostic Significance for FAM83 Family in Non-small-Cell Lung Cancer.

ABSTRACT:

Background

Lung cancer remains a common malignancy and the leading cause of cancer-related deaths in the world. Although dramatic progress made in multimodal therapies, it still has a poor prognosis. The Family with sequence similarity 83 (FAM83) of poorly characterized proteins are defined by the presence of the conserved DUF1669 domain of unknown function at their N-termini, most of which significantly elevated levels of expression in multiple cancers. However, the expression and prognostic values of different FAM83 family in lung cancer, especially in non-small-cell lung cancer (NSCLC), have not been clarified.

Methods

ONCOMINE, UALCAN, GEPIA, Kaplan-Meier Plotter, cBioPortal, and STRING databases were utilized in this study.

Results

The transcription

SUBMITTER: Gan J 

PROVIDER: S-EPMC7758490 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature