Association of Histologic Regression With a Favorable Outcome in Patients With Stage 1 and Stage 2 Cutaneous Melanoma.

ABSTRACT:

Importance

Although regression is commonly observed in cutaneous melanoma, it is uncertain whether it is associated with patient prognosis.

Objective

To determine whether histologically confirmed regression was associated with better or worse survival in patients with primary cutaneous melanoma.

Design, setting, and participants

This cohort study analyzed data from 2 large cohorts of adults (one in the Netherlands and the other in Australia) with histologically proven, stage 1 and 2 primary, invasive cutaneous melanoma with known regression status treated between 2000 and 2014, with median follow-up times of 4.5 and 11.1 years for the Dutch and Australian cohorts, respectively. For the Dutch patients, population-based data from PALGA, the Dutch Pathology Registry, wer

SUBMITTER: El Sharouni MA 

PROVIDER: S-EPMC7758823 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature