The risk of polypharmacy, comorbidities and drug-drug interactions in women of childbearing age with multiple sclerosis.

ABSTRACT:

Background and aims

Multiple sclerosis (MS) is the most common neuroimmunological disease of the central nervous system in young adults. Despite recommended contraception, unplanned pregnancies can occur in women of childbearing age with MS. MS- and comorbidities-related multimedication in these patients represents a potential risk. We aimed to raise awareness regarding the frequency of polypharmacy and drug-drug interactions (DDIs) in female MS patients of childbearing age.

Methods

Sociodemographic, clinical and pharmaceutical data were collected through patient records, clinical investigations and structured patient interviews of 131 women with MS. The clinical decision support software MediQ was used to identify potential DDIs. A medication and DDI profile of the study po

SUBMITTER: Frahm N 

PROVIDER: S-EPMC7758868 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature