Path Integration and Cognitive Mapping Capacities in Down and Williams Syndromes.

ABSTRACT: Williams (WS) and Down (DS) syndromes are neurodevelopmental disorders with distinct genetic origins and different spatial memory profiles. In real-world spatial memory tasks, where spatial information derived from all sensory modalities is available, individuals with DS demonstrate low-resolution spatial learning capacities consistent with their mental age, whereas individuals with WS are severely impaired. However, because WS is associated with severe visuo-constructive processing deficits, it is unclear whether their impairment is due to abnormal visual processing or whether it reflects an inability to build a cognitive map. Here, we tested whether blindfolded individuals with WS or DS, and typically developing (TD) children with similar mental ages, could use path integration to perfor

SUBMITTER: Bostelmann M 

PROVIDER: S-EPMC7759488 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature