Candida Species (Volatile) Metabotyping through Advanced Comprehensive Two-Dimensional Gas Chromatography.

ABSTRACT: Microbial metabolomics is a challenge strategy that allows a comprehensive analysis of metabolites within a microorganism and may support a new approach in microbial research, including the microbial diagnosis. Thus, the aim of this research was to in-depth explore a metabolomics strategy based on the use of an advanced multidimensional gas chromatography for the comprehensive mapping of cellular metabolites of C. albicans and non-C. albicans (C. glabrata and C. tropicalis) and therefore contributing for the development of a comprehensive platform for fungal detection management and for species distinction in early growth times (6 h). The volatile fraction comprises 126 putatively identified metabolites distributed over several chemical families: acids, alcohols, aldehydes, hydrocarbons, e

SUBMITTER: Costa CP 

PROVIDER: S-EPMC7760324 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature