New Insights into the Microbial Profiles of Infected Root Canals in Traumatized Teeth.

ABSTRACT: Traumatic dental injuries in young individuals are often exposed to the invasion of oral microorganisms that leads to pulp necrosis. Infective necrosis in permanent teeth not-fully-developed causes aberrant root formation. Regeneration endodontic treatments (RETs) have shown promising results by promoting continued root development by stem cells. Critical to the success of RET is the thorough disinfection of the pulpal space. To establish effective antimicrobial protocols for root canal disinfection, the invading microorganisms need to be identified. In the present study, we use a combination of culture-based and high-throughput molecular sequencing techniques to investigate the microbial profiles from traumatized teeth (30 cases) and controls, i.e., teeth with pulp infections not caused b

SUBMITTER: Manoharan L 

PROVIDER: S-EPMC7760719 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature