BingleSeq: a user-friendly R package for bulk and single-cell RNA-Seq data analysis.

ABSTRACT:

Background

RNA sequencing is an indispensable research tool used in a broad range of transcriptome analysis studies. The most common application of RNA Sequencing is differential expression analysis and it is used to determine genetic loci with distinct expression across different conditions. An emerging field called single-cell RNA sequencing is used for transcriptome profiling at the individual cell level. The standard protocols for both of these approaches include the processing of sequencing libraries and result in the generation of count matrices. An obstacle to these analyses and the acquisition of meaningful results is that they require programing expertise. Although some effort has been directed toward the development of user-friendly RNA-Seq analysis analysis tools, few ha

SUBMITTER: Dimitrov D 

PROVIDER: S-EPMC7761193 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature