Vitamin C-An Adjunctive Therapy for Respiratory Infection, Sepsis and COVID-19.

ABSTRACT: There are limited proven therapies for COVID-19. Vitamin C's antioxidant, anti-inflammatory and immunomodulating effects make it a potential therapeutic candidate, both for the prevention and amelioration of COVID-19 infection, and as an adjunctive therapy in the critical care of COVID-19. This literature review focuses on vitamin C deficiency in respiratory infections, including COVID-19, and the mechanisms of action in infectious disease, including support of the stress response, its role in preventing and treating colds and pneumonia, and its role in treating sepsis and COVID-19. The evidence to date indicates that oral vitamin C (2-8 g/day) may reduce the incidence and duration of respiratory infections and intravenous vitamin C (6-24 g/day) has been shown to reduce mortality, intensiv

SUBMITTER: Holford P 

PROVIDER: S-EPMC7762433 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature