Distinct phenotypic characteristics of normal-weight adults at risk of developing cardiovascular and metabolic diseases.

ABSTRACT:

Background

The normal-weight BMI range (18.5-24.9 kg/m2) includes adults with body shape and cardiometabolic disease risk features of excess adiposity, although a distinct phenotype developed on a large and diverse sample is lacking.

Objective

To identify demographic, behavioral, body composition, and health-risk biomarker characteristics of people in the normal-weight BMI range who are at increased risk of developing cardiovascular and metabolic diseases based on body shape.

Methods

Six nationally representative waist circumference index (WCI, weight/height0.5) prediction formulas, with BMI and age as covariates, were developed using data from 17,359 non-Hispanic (NH) white, NH black, and Mexican-American NHANES 1999-2006 participants. These equations were then used

SUBMITTER: Stanley A 

PROVIDER: S-EPMC7762762 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature