Noxious pressure stimulation demonstrates robust, reliable estimates of brain activity and self-reported pain.

ABSTRACT: Functional neuroimaging techniques have provided great insight in the field of pain. Utilising these techniques, we have characterised pain-induced responses in the brain and improved our understanding of key pain-related phenomena. Despite the utility of these methods, there remains a need to assess the test retest reliability of pain modulated blood-oxygen-level-dependant (BOLD) MR signal across repeated sessions. This is especially the case for more novel yet increasingly implemented stimulation modalities, such as noxious pressure, and it is acutely important for multi-session studies considering treatment efficacy. In the present investigation, BOLD signal responses were estimated for noxious-pressure stimulation in a group of healthy participants, across two separate sessions. Test r

SUBMITTER: Jackson JB 

PROVIDER: S-EPMC7762811 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature