Alertness fluctuations when performing a task modulate cortical evoked responses to transcranial magnetic stimulation.

ABSTRACT: Transcranial magnetic stimulation (TMS) has been widely used in human cognitive neuroscience to examine the causal role of distinct cortical areas in perceptual, cognitive and motor functions. However, it is widely acknowledged that the effects of focal cortical stimulation can vary substantially between participants and even from trial to trial within individuals. Recent work from resting state functional magnetic resonance imaging (fMRI) studies has suggested that spontaneous fluctuations in alertness over a testing session can modulate the neural dynamics of cortical processing, even when participants remain awake and responsive to the task at hand. Here we investigated the extent to which spontaneous fluctuations in alertness during wake-to-sleep transition can account for the variabil

SUBMITTER: Noreika V 

PROVIDER: S-EPMC7762840 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature