MRNA Expression and Role of PPARγ and PPARδ in Bovine Preimplantation Embryos Depending on the Quality and Developmental Stage.

ABSTRACT: Peroxisome proliferator-activated receptors (PPARs), a nuclear receptors for prostacyclin (PGI₂) have been recognized as being essential for early embryo development. The objectives of the present study were to determine if the bovine early- and late-cleaved embryos in different stages of early development express PPARγ and PPARδ. Since embryo developmental competence depends on numerous biological factors, we evaluated if the expression of PPARγ and PPARδ correlate with selected embryo quality markers (SOX2, OCT4, PLAC8, IGF1R) in the in vitro produced embryos at different stages of their development. Developmental rates and embryo quality for early- and late-cleaved embryos were provided according to International Embryo Transfer Society (IETS; developmental stages: 2-, 4-, 16

SUBMITTER: Suwik K 

PROVIDER: S-EPMC7763280 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature