COVID-19 and Acute Kidney Injury: A Systematic Review and Meta-Analysis.

ABSTRACT: coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)-is an ongoing pandemic with high morbidity and mortality rates. Preliminary evidence suggests that acute kidney injury (AKI) is uncommon in patients with COVID-19 and associated with poor outcomes. Study aims and design: we performed a systematic review of the literature with a meta-analysis of clinical studies to evaluate the frequency of AKI and dialysis requirement in patients who underwent hospitalization due to COVID-19. The incidence of AKI according to the death risk was calculated in these patients. The random-effects model of DerSimonian and Laird was adopted, with heterogeneity and stratified analyses. thirty-nine clinical studies (n = 25,566 unique patients) were retrieved

SUBMITTER: Fabrizi F 

PROVIDER: S-EPMC7765425 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature