Distinct African Swine Fever Virus Shedding in Wild Boar Infected with Virulent and Attenuated Isolates.

ABSTRACT: Since the reappearance of African swine fever virus (ASFV), the disease has spread in an unprecedented animal pandemic in Eurasia. ASF currently constitutes the greatest global problem for the swine industry. The wild boar (Sus scrofa) in which the pathogen has established wild self-sustaining cycles, is a key reservoir for ASFV, signifying that there is an urgent need to develop an effective vaccine against this virus. Current scientific debate addresses whether live attenuated vaccines (LAVs), which have shown promising results in cross-protection of susceptible hosts, may be feasible for vaccinations carried out owing to safety concerns. The objective of this study was, therefore, to compare the ASFV shedding in wild boar infected with virulent and attenuated (LAV) isolates. Different s

SUBMITTER: Kosowska A 

PROVIDER: S-EPMC7765575 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature