Association of Primary Sjogren's Syndrome and Vitamin B12 Deficiency: A Cross-Sectional Case-Control Study.

ABSTRACT: Descriptive and retrospective studies without control groups have suggested a possible association between primary Sjögren's syndrome (pSS) and vitamin B12 (B12) deficiency. This is of importance because several mucosal and neurological features are common to these two conditions and could be prevented or reversed in case of B12 deficiency. We aimed to evaluate the association between pSS and B12 deficiency. We prospectively assessed the B12 status of 490 patients hospitalized in an internal medicine department over a 15-week period. Patients with pernicious anemia were excluded. We extracted patients with pSS and paired them with controls according to age and sex, with a 1:5 ratio. Twenty-one pSS patients were paired with 105 control patients. The median age was 70 years old (51-75) and 9

SUBMITTER: Urbanski G 

PROVIDER: S-EPMC7765802 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature