Local Vascularization during Orthodontic Tooth Movement in a Split Mouth Rat Model-A MRI Study.

ABSTRACT: Orthodontic tooth movement to therapeutically align malpositioned teeth is supposed to impact blood flow in the surrounding tissues. Here, we evaluated actual vascularization in the tension area of the periodontal ligament during experimental tooth movement in rats (N = 8) with magnetic resonance imaging (MRI). We inserted an elastic band between the left upper first and the second rat molar; the right side was not treated and served as control. After four days of tooth movement, we recorded T1-weighted morphologic and dynamic-contrast-enhanced MRI sequences with an animal-specific 7 Tesla MRI to assess of local vascularization. Furthermore, we quantified osteoclasts and monocytes in the periodontal ligament, which are crucial for orthodontic tooth movement, root resorptions as undesirable

SUBMITTER: Proff P 

PROVIDER: S-EPMC7766506 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature