Metabolomics for Diagnosis and Prognosis of Uterine Diseases? A Systematic Review.

ABSTRACT: This systematic review analyses the contribution of metabolomics to the identification of diagnostic and prognostic biomarkers for uterine diseases. These diseases are diagnosed invasively, which entails delayed treatment and a worse clinical outcome. New options for diagnosis and prognosis are needed. PubMed, OVID, and Scopus were searched for research papers on metabolomics in physiological fluids and tissues from patients with uterine diseases. The search identified 484 records. Based on inclusion and exclusion criteria, 44 studies were included into the review. Relevant data were extracted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) checklist and quality was assessed using the QUADOMICS tool. The selected metabolomics studies analysed plasm

SUBMITTER: Tokarz J 

PROVIDER: S-EPMC7767462 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature