ComPIL 2.0: An Updated Comprehensive Metaproteomics Database.

ABSTRACT: We designed a metaproteomic analysis method (ComPIL) to accommodate the ever-increasing number of sequences against which experimental shotgun proteomics spectra could be accurately and rapidly queried. Our objective was to create these large databases for the analysis of complex metasamples with unknown composition, including those derived from human, animal, and environmental microbiomes. The amount of high-throughput sequencing data has substantially increased since our original database was assembled in 2014. Here, we present a rebuild of the ComPIL libraries comprised of updated publicly disseminated sequence data as well as a modified version of the search engine ProLuCID-ComPIL optimized for querying experimental spectra. ComPIL 2.0 consists of 113 million protein records and roughl

SUBMITTER: Park SKR 

PROVIDER: S-EPMC7767584 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature