In silico ranking of phenolics for therapeutic effectiveness on cancer stem cells.

ABSTRACT:

Background

Cancer stem cells (CSCs) have features such as the ability to self-renew, differentiate into defined progenies and initiate the tumor growth. Treatments of cancer include drugs, chemotherapy and radiotherapy or a combination. However, treatment of cancer by various therapeutic strategies often fail. One possible reason is that the nature of CSCs, which has stem-like properties, make it more dynamic and complex and may cause the therapeutic resistance. Another limitation is the side effects associated with the treatment of chemotherapy or radiotherapy. To explore better or alternative treatment options the current study aims to investigate the natural drug-like molecules that can be used as CSC-targeted therapy. Among various natural products, anticancer potential of phen

SUBMITTER: Mandal M 

PROVIDER: S-EPMC7768647 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature