Two decades of the Eurotransplant Senior Program: the gender gap in mortality impacts patient survival after kidney transplantation.

ABSTRACT:

Background

Long-term outcomes of the Eurotransplant Senior Program (ESP) are urgently needed to improve selection criteria and allocation policies in the elderly.

Methods

We analysed patient and allograft outcomes of 244 ESP-kidney transplant recipients (KTRs) between 1999 and 2019 and assessed quality of living compared with 82 ESP-waitlisted dialysis patients using standardized short form-8.

Results

We observed 1-, 5- and 10-year patient survival of 91.7, 66.3 and 38.0%, respectively. Mortality risk factors included male gender (P = 0.006) and T-cell-mediated rejection (P < 0.001). Median patient survival of male ESP-KTRs was 80 versus 131 months for female ESP-KTRs (P = 0.006). 1-, 5- and 10-year death-censored allograft survival was 93.3, 82.6 and 70.4%. Risk fact

SUBMITTER: Schachtner T 

PROVIDER: S-EPMC7769544 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature