A dynamic, ring-forming MucB / RseB-like protein influences spore shape in Bacillus subtilis.

ABSTRACT: How organisms develop into specific shapes is a central question in biology. The maintenance of bacterial shape is connected to the assembly and remodelling of the cell envelope. In endospore-forming bacteria, the pre-spore compartment (the forespore) undergoes morphological changes that result in a spore of defined shape, with a complex, multi-layered cell envelope. However, the mechanisms that govern spore shape remain poorly understood. Here, using a combination of fluorescence microscopy, quantitative image analysis, molecular genetics and transmission electron microscopy, we show that SsdC (formerly YdcC), a poorly-characterized new member of the MucB / RseB family of proteins that bind lipopolysaccharide in diderm bacteria, influences spore shape in the monoderm Bacillus subtilis. Sp

SUBMITTER: Luhur J 

PROVIDER: S-EPMC7769602 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature