Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data.

ABSTRACT:

Background

People with reduced kidney function have increased cardiovascular disease (CVD) risk. We present a policy model that simulates individuals' long-term health outcomes and costs to inform strategies to reduce risks of kidney and CVDs in this population.

Methods and findings

We used a United Kingdom primary healthcare database, the Clinical Practice Research Datalink (CPRD), linked with secondary healthcare and mortality data, to derive an open 2005-2013 cohort of adults (≥18 years of age) with reduced kidney function (≥2 measures of estimated glomerular filtration rate [eGFR] <90 mL/min/1.73 m2 ≥90 days apart). Data on individuals' sociodemographic and clinical characteristics at entry and outcomes (first occurrences of stroke, myocardial infarction (MI), and hospit

SUBMITTER: Schlackow I 

PROVIDER: S-EPMC7769604 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature