Novel Gallium(III), Germanium(IV), and Hafnium(IV) Folate Complexes and Their Spectroscopic, Thermal Decomposition, Morphological, and Biological Characteristics.

ABSTRACT: In this study, we describe novel gallium(III), germanium(IV), and hafnium(IV) folate complexes, including their synthesis and analyses. The synthesized folate complexes were also subject to thermal analysis (TGA) to better examine their thermal degradation and kinetic properties. The folate complexes had high stability and were nonspontaneous. The Coats-Redfern and Horowitz-Metzger equations were used to determine thermodynamic parameters and describe the kinetic properties. These complexes were synthesized through the chemical interactions in neutralized media between the folic acid drug ligand (FAH₂) with GaCl₃, GeCl₄, and HfCl₄ metal salts at 1 : 2 (metal : ligand) molar ratio. The conductance measurements have low values due to their nonelect

SUBMITTER: El-Habeeb AA 

PROVIDER: S-EPMC7769666 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature