Microbiome-gut-brain axis in cancer treatment-related psychoneurological toxicities and symptoms: a systematic review.

ABSTRACT:

Purpose

The microbiome-gut-brain (MGB) axis provides a dynamic model to understand associations between the gut microbiota and psychoneurological comorbidities. The role of the MGB axis in cancer treatment-related psychoneurological symptoms (PNS) remains unknown. The purpose of this study was to conduct a systematic review of the existing literature to identify the influence of the gut microbiota on cancer and cancer treatment-related PNS and toxicities mediated by the MGB axis.

Methods

We searched the databases of PubMed, Embase, and Web of Science from their earliest records to October 2019. All studies identified in the database searches were screened by title and abstract, followed by a review of the full texts. The Johns Hopkins Nursing Evidence-Based Practice Model wa

SUBMITTER: Song BC 

PROVIDER: S-EPMC7769970 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature