Recurrent versus new-onset depressive symptoms: Relationships with biomarkers of cardiovascular health following acute coronary syndrome.

ABSTRACT:

Objective

New-onset depressive symptoms commonly arise among persons without a history of major depressive disorder (MDD) in the setting of acute medical illness. Although depressive symptoms in general are associated with alterations in prognostic biomarkers following acute coronary syndrome (ACS), the nature of specifically new-onset depressive symptoms is less well-characterized. It is unclear whether such symptoms neurobiologically resemble recurrent symptoms of MDD or instead represent a distinct condition. In this exploratory analysis, we aimed to examine the effects of prior MDD history on the relationships between post-ACS depressive symptoms and cardiovascular biomarkers.

Methods

One-hundred sixty-four participants attended study visits 2 weeks and 6 months after AC

SUBMITTER: Madva EN 

PROVIDER: S-EPMC7770037 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature